O100
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O100
Sigma
Oxotremorine M
solid
| Synonym: | Oxotremorine methiodide, N,N,N,-Trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-ammonium iodide |
| CAS Number: | 63939-65-1 |
| Linear Formula: | C11H19IN2O |
| Molecular Weight: | 322.19 |
| MDL number: | MFCD00055133 |
| PubChem Substance ID: | 24277861 |
Description
| Biochem/physiol Actions | Nonselective muscarinic acetylcholine receptor agonist. |
Properties
| form | solid |
| color | white |
| solubility | H2O: 24 mg/mL |
| ethanol: 4.6 mg/mL | |
| Gene Information | human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133) |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | ER9552000 |
References
| reference | Tayebati, S.K., Evaluation of an agonist index: affinity ratio for compounds active on muscarinic cholinergic M2 receptors. J. Auton. Pharmacol. 19, 77, (1999) Abstract |
| Gillard, M., Muscarinic receptor heterogeneity in rat central nervous system. II. Brain receptors labeled by [3H]oxotremorine-M correspond to heterogeneous M2 receptors with very high affinity for agonists. Mol. Pharmacol. 32, 100, (1987) Abstract |
